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The Korean Journal of Pathology 1974;8(2): 123-129.
식물혈구응집소 Eugenia c.t.가 실혈가토의 조혈기능에 미치는 영향
Effect of Eugenia c. t. on Hematopoietic Activity of Bleeded Rabbit
ABSTRACT
Eugenia caryophyllata tumberg (ECT) has been known to have possessed phytohemagglutinin activity. This study was undertaken to evaluate whether ECT has an effect on the erythropoietic activity. Rabbits of experimental group were injected 1.0ml. of ECT extract intravenously just after bleeding and studied peripheral blood in R.B.C. count, hematocrit, reticulocyte count, hemoglobin, total W.B.C. count, lymphocyte and granulocyte count. The results obtained are as follow: 1. Marked decrease in R.B.C. count, hemoglobin and hematocrit were noted on the first and second day after ECT injection. 2. Hematologic data which was decreased previously showed tendency to recover from third day after injection, and it recovered to the values of pre-bleeding on the tenth day after injection. 3. Considerable increase in reticulocyte count was observed from the first day after injection and it reached maximum level on the seventh day. But increased levels kept sustained on the thirteenth day. 4. Total leukocyte count was increased about 86% on the first day, 130% on the second day after injection and it recovered to the value of pre-bleeding on forth day after injection. 5. Increase of total leukocyte count was due to mainly increased number of lymphocytes and granulocytes in peripheral blood. 6. ECT seems to have erythroagglutinin at earlier stage and potency to stimulate erythropoietic activities at later stage and it seems to increase in peripheral lymphocyte of rabbit.
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