Abstract

Many publications for correlative studies and a possible relationship of benign conditions and carcinoma of the breasts have been reported for many years. Quite recently 1974, there has been presented the atypical lesion as precancerous lesion of the breast. For this interesting reason, histopathologic study of atypical lesion was performed to compare frequency both in the benign lesions and in the remaining tissues of breast cancer, for 15 years from Jan. 1960 to Sept. 1974, with the histopathologic criteria by Ashikari et al. (1974) A total of 17 cases of atypical lesion were found both in the benign and cancer breasts; the mean age was 45; there were found in 3% of the benign breast lesions and in 5.5% of the remaining breast tissues of breast cancer. The conditions of periductal elastic fiber in atypical lesion are found without difference from the other benign breast lesions. It is not certain that this is definitely precancerous with this limited study, but it can be assumed that this is probably precancerous, and that a special attention both for pathologists and surgeons should be necessary.