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The Korean Journal of Pathology 1976;10(2): 261-269.
충양돌기에 검액성종양
Mucinous Neoplasm of the Appendix (A re-evaluation of 7 Cases of Appendiceal Mucoceles)
The designation of mucocele has been traditionally applied to a group of appendiceal lesions characterized by one or more of the following features ; (1) dilatation of the lumen, (2) alterations of the mucosal lining, (3) hypersecretion of mucus, and (4) occasional extension outside the appendix, either as peritoneal implants or exceptionally as distant metastatic spread. The re-evaluation of 7 appenaiceal mucoceles, examined at Department of Pathology, National Medical Center, Seoul, during 17 years from March 1959 to July 1976, was made and showed four distinctive clinicopathologic entities : 1) Secondary mucosal atrophy resulting from proximal luminal obliteration (1 case), accompanied with volvulus. 2) Focal mucosal hyperplasia (1 case), with no epithelial atypia. This case was associated with mucinous adenocarcinoma of cecum. 3) Mucinous cystadenoma (4 cases). Two of these reveal slight degree of cellular atypia and some acellular mucus in peritoneal cavity without adhesion. Remaining two show mucosal ulceration of appendico-cecal junction. 4) Mucinous cystadenocarcinoma (1 case). This case shows focal stromal invasion by atypical glands and/or epithelial cells, also seen in peritoneal implants. On the basis of these findings, most instances of so-called mucocele should be regarded as mucinous neoplasms, analogous in many aspects to the epithelial tumors of the colon, and those diagnostic distinction is justified on practical grounds, since it provides the pathologist and the surgeon with definite criteria on which base prognostic and therapeutic consideration.
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