Abstract

The authors investigated serum HBsAg and anti-HBsAg by methods of counterimmunoelectrophoresis(CIEP) and reverses passive hemagglutination(r-PHA) and passive hemagglutination(PHA) The sera were obtained from 1502 cases of healthy control, 530 cases of acute liver damage and 480 cases of chronic liver damage in Busan National University Hospital during the year of 1977. We compared serum HBsAg and anti-HBsAg positive rates between two methods and the following results were obtained. 1. In the healthy control, acute and chronic liver damage, serum HBsAg positive rates 4.5, 17.1 and 22.9% by R-PHA were significantly higher than those 2.3, 5.3 and 9.2% by CIEP, respectively. 2. In the healthy control, acute and chronic liver damage, serum anti-HBsAg positive rates 13.8, 14.9 and 17.5% by PHA were significantly higher than those 0.3, 0.4 and 1.5% by CIEP, respectively. On the basis of above mentioned results, R-PHA and PHA tests proved to be more sensitive than CIEP in detection of serum HBsAg and anti-HBsAg.