Several tests for detection of penicillinase have been devised to the present time but most of them are too cumbersome or too time consuming for routine hospital use. Recently, Rosenblatt et al. developed a rapid slide test which is a modification of the iodometric method. The authors examined 130 strains of S.aureus and 70 strains of S. epidermidis isolated from clinical specimens using this slide method and compared these results with those of Workman and Farrar's agar plate method and disk diffusion susceptibility test against penicillin G. All of the penicillinase-positive staphylococci were resistant to penicillin G. However peincillinase-negative staphylococci were not always sensitive to penicillin G. Therefore the susceptibility test were needed in this cases.