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The Korean Journal of Pathology 1980;14(4): 56-61.
Glanzmann's Thrombasthenia 3예 보고
Glanzmann's Thrombasthenia -Report of three patients-
ABSTRACT
Thrombasthenia is a rare disorder, apparently transmitted as an autosomal recessive trait, in which platelet count is normal but bleeding time is greatly prolonged and clot retraction is defective. The chief clinical finding is a tendency to develop purpura and ecchymosis on trivial injury from early childhood but visceral hemorrhage and hemarthroses are rare. Epistaxes are common. The most striking feature, which is pathognomonic of this disease, is a complete failure of the platelets to aggregate in response to any concentration of ADP, epinephrine ana collagen. The three cases, which meet the diagnostic criteria of Glanzmann's thrombasthenia, are reported with review of the literatures.
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