| Home | E-Submission | Sitemap | Contact Us |  

The Korean Journal of Pathology 1980;14(4): 62-68.
개심술 환자에 있어서의 혈청 Creatinine Phosphokinase Isoenzyme 분획상
Serum Creatine Phosphokinase Isoenzymes in Open Heart Patients
ABSTRACT
Total CPK and the heart-specific isoenzyme of creatine phosphokinase(CPK-MB) values have been studied during operative and postoperative periods in 13 patients undergoing open heart surgery, using cellulose acetate electrophoresis. The results were: 1) Total CPK value of normal control group was 29±6.0 U/L (mean±S.D.) and only MM-fraction was observed. 2) Preoperative total CPK value was 49±50.7 U/L(mean±S.D.) and preoperative MB-fraction was not detected in most patients(l1/13), but detected in two patients(2/13). 3) Peak total CPK activity appeared from pump stop to 2nd postoperative day(39∼49 hours from pump stop) and gradually declined to normal activity by 6th postoperative day. 4) CPK-MB was first detectable during the period of cardiopulmonary bypass in about 46% of cases(6/13). 5) Peak MB isoenzyme was demonstrable during the period of pump stop to 1st postoperative day(16∼25 hours from pump stop) in 12 cases out of 13. 6) Duration of sustained CPK-MB showed no correlation with cardiopulmonary bypass and aortic cross-clamping time. 7) In cases showing relatively persistant CPK-MB, the peak total CPK and MB isoenzyme values were higher and remained for longer period of time, than transient CPK-MB group. 8) 2 cases showing preoperative CPK-MB died postoperatively.
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
  E-Mail
Share:      
METRICS
1,055
View
10
Download
Related article
Electrophoretic Patterns of Serum Alkaline Phosphatase Isoenzyme in Liver Diseases  1978 December;12(4)