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The Korean Journal of Pathology 1981;15(1): 23-28.
정상 및 질환군에서의 HDL-cholesterol치에 관한 연구
A Study on HDL-chotesterol Levels in Normal and Disease Conditions
More than 25 years ago, Barr et al noted the negative relationship between high density lipoprotein (HDL) and the incidence of coronary artery disease. A number of studies supported for it. Recently it was known that HDL-cholesterol is more useful indicator of coronary heart disease than total cholesterol and triglyceride. Author studied the difference of HDL-cholesterol levels and HDL-cholesterol/total cholesterol ratio between normal male and female subjects, and HDL-cholesterol level in patients of coronary heart disease, diabetes mellitus, liver disease and gastrointestinal malignancies. The results are as follows: 1) Mean HDL-cholesterol level of normal subjects was 44.7± 12.4 mg/d1 and those of female and male were 48.7±14.2 mg/dl and 41.9±10.1 mg/dl respectively. 2) HDL-cholesterol/total cholesterol ratio in female was higher than that of male. 3) HDL-cholesterol level in normal subjects showed no significant changes with age. 4) The difference between HDL-cholesterol levels in patients of coronary heart disease and diabetes mellitus and that of normal subjects was insignificant. 5) HDL-cholesterol levels in patients of liver disease and gastrointestinal malignancies were lower than normal subjects.
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