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The Korean Journal of Cytopathology 1996;7(1): 97-102.
Fine Needle Aspiration Cytology of Metastatic Pulmonary Seminoma: A Cese Report.
Hwa Sook Jeong, Geon Kook Lee, Wun Jae Kim, Jae Ho Earm, Hyung Geun Song
1Department of Pathology, College of Medicine, Chungbuk National University, Korea.
2Department of Urology, College of Medicine, Chungbuk National University, Korea.
3Department of Internal Medicine, College of Medicine, Chungbuk National University, Korea.
ABSTRACT
Fine needle aspiration cytologyof a pulmonary mass was performed on a 51-year-old man who had a left testicular mass. Cytologic features were composed of a homogeneous population of malignant cells associated with a background of foamy and lacelike material. The cellular features were characterized by monomorphous cell proliferation of relatively regular large cells, generally isolated or grouped. Occasionally, fine branching stroma with large tumor cells and scanty lymphocytes were noted. The tumor cells had a round, regular nucleus, prominent round nucleoli, and a thin rim of cytoplasm containing large vacuoles or lacunae filled with glycogen. The fine needle aspiration cytologic diagnosis was highly consistent with metastatic seminoma from testis and less likely primary or other metastatic carcinoma. The diagnosis of resected testicular mass was classic seminoma. Despite the fact that cytopathologists were not familiar with diagnosis of seminoma due to clinician's lack of interest in fine needle aspiration cytology of germ cell tumors including seminoma, it appears that a diagnosis of this tumor should not be problematic in cytologic material if specific histologic criteria are applied.
Key Words: Fine needle aspiration cytology; Seminoma; Metastasis; Lung