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The Korean Journal of Pathology 1999;33(7): 537-539.
Balloon Cell Malignant Melanoma: A case report.
Ji Young Seo, Soon Young Kim, Jeong Hee Kang, Young Ok Kim, Bang Hur
1Department of Pathology, Kosin Medical College of University.
2Dong Masan Hospital, Pusan 602-702, Korea.
ABSTRACT
Balloon cell malignant melanoma (BCMM) is a rare histologic variant of malignant melanoma, which is composed either predominantly or entirely of large clear or foamy cells. The incidence of balloon cell malignant melanoma is about 0.15% of all cutaneous malignant melanomas. Recently, we experienced a case of cutaneous balloon cell malignant melanoma in the right lower abdomen with right inguinal and both axillary lymph node metastasis in a 56-year-old man. The cutaneous lesion was 4.5 3.5 cm in size, a well-demarcated black nodular mass, involving abdominal skin and subcutaneous tissue. The tumor was histologically composed of two types of tumor cells: predominant clear cell and focal, pigmented spindle cell. The nodal lesion was composed entirely of clear cells. Both clear and spindle cells showed positive reaction for S-100 protein and HMB-45 on immunohistochemistry.
Key Words: Malignant melanoma; Balloon cell
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