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The Korean Journal of Pathology 2003;37(3): 151-158.
Experimental Liver Disease Models of Rats: Morphological Characteristics.
Do Youn Park, Kang Suek Suh
Department of Pathology, College of Medicine, Pusan National University, Busan, Korea. pdy220@pusan.ac.kr
Experimental liver disease models of rats have many similarities with those of humans, especially in morphological characteristics. Rat liver disease models can be categorized as models of hepatic fibrosis, hepatic stem cell and hepatocarcinogenesis. The purpose of this article is to review experimental liver disease models, with a major emphasis on morphologic features, including routine morphological, immunohistochemical, and electron microscopic features.