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HOME > J Pathol Transl Med > Volume 45(1); 2011 > Article
Case Report Lipofibromatosis: A Case Report.
Tae Eun Kim, Tae Jung Kim, Youn Soo Lee, Chang Suk Kang, Sang In Shim, Kyo Young Lee
Journal of Pathology and Translational Medicine 2011;45(1):106-110
DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.1.106
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Department of Hospital Pathology, The Catholic University of Korea School of Medicine, Seoul, Korea. kimecho@catholic.ac.kr

Lipofibromatosis is a recently described rare benign fibrofatty tumor of childhood. It typically forms as an ill defined, slowly growing, painless mass. We present here the case of lipofibromatosis that occurred in a 21-year-old male who had complained of a bulging enlarged mass involving the right thigh and prepatella area for the previous 1 year. Magnetic resonance imaging showed an ill-defined reticular infiltration in the subcutaneous layer with subtle linear enhancement and high T2 signal intensity. The mass was surgically excised and it displayed an 11.0x5.5x1.5 cm-sized adipose appearance without encapsulation. Microscopically, the tumor was composed of alternating streaks of mature adipose tissue and a fibroblastic component that mainly involved the septa of adipose tissue. On immunohistochemical study, the fibroblastic component was positive for S-100, CD99, CD34, actin and bcl-2. He has shown an eventful recovery for 6 months after surgery.

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