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The Korean Journal of Pathology 2011;45(1): 106-110.
doi: https://doi.org/10.4132/KoreanJPathol.2011.45.1.106
Lipofibromatosis: A Case Report.
Tae Eun Kim, Tae Jung Kim, Youn Soo Lee, Chang Suk Kang, Sang In Shim, Kyo Young Lee
Department of Hospital Pathology, The Catholic University of Korea School of Medicine, Seoul, Korea. kimecho@catholic.ac.kr
ABSTRACT
Lipofibromatosis is a recently described rare benign fibrofatty tumor of childhood. It typically forms as an ill defined, slowly growing, painless mass. We present here the case of lipofibromatosis that occurred in a 21-year-old male who had complained of a bulging enlarged mass involving the right thigh and prepatella area for the previous 1 year. Magnetic resonance imaging showed an ill-defined reticular infiltration in the subcutaneous layer with subtle linear enhancement and high T2 signal intensity. The mass was surgically excised and it displayed an 11.0x5.5x1.5 cm-sized adipose appearance without encapsulation. Microscopically, the tumor was composed of alternating streaks of mature adipose tissue and a fibroblastic component that mainly involved the septa of adipose tissue. On immunohistochemical study, the fibroblastic component was positive for S-100, CD99, CD34, actin and bcl-2. He has shown an eventful recovery for 6 months after surgery.
Key Words: Fibroma; Thigh; Adolescent; Adipose tissue; Lipoma
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