Childhood Asymmetry Labium Majus Enlargement.

Mi Jin Gu; Sang Yoon Kim

doi:10.4132/KoreanJPathol.2011.45.5.529

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Case Report Childhood Asymmetry Labium Majus Enlargement.: Mi Jin Gu, Sang Yoon Kim; Journal of Pathology and Translational Medicine 2011;45(5):529-531
DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.5.529

¹Department of Pathology, Daegu Fatima Hospital, Daegu, Korea. gmjap@fatima.or.kr
²Department of Surgery, Daegu Fatima Hospital, Daegu, Korea.

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Abstract

Childhood asymmetry labium majus enlargement (CALME) is a disctinctive clinicopathologic entity of pre- and early puberty first described in 2005. It is defined as an expansion of normal soft tissues of the vulva. Although CALME is not a rare lesion, it has been called lipoma, fibroma, hamartoma, and fibrous hyperplasia. CALME is not a true neoplasm and is a physiologic growth in response to hormone. It may tend to resolve spontaneously and recur after surgical resection. We report four cases of CALME with a review of the literature. To the best of the knowledge, this is the first Korean report.

Keywords: Child;Vulva;Hypertrophy;Enlargement;Puberty

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