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The Korean Journal of Cytopathology 2007;18(1): 62-68.
Fine Needle Aspiration Cytology of Invasive Micropapillary Carcinoma of the Breast.
Hyun Joo Choi, Ji Han Jung, Jung Ha Shin, Kiouk Min, Jinyoung Yoo, Seok Jin Kang, Kyo Young Lee
Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea. jinyyoo@vincent.cuk.ac.kr
Invasive micropapillary carcinoma (IMPC) of the breast is recently described rare variant of invasive ductal carcinoma. This variant has a distinctive histological features and aggressive biological behavior. We reviewed the cytologic features of eight cases of IMPC. The cytologic smears showed moderate to high cellularity and the tumor tissue was composed of atypical, angulated, cohesive clusters of neoplastic cells with a papillary to tubuloalveolar architecture, and a morular growth pattern without fibrovascular cores was seen on the histopathology. IMPC of the breast has distinctive cytologic features and it is important to make an early diagnosis via fine needle aspiration cytology due to this tumor's aggressive behavior.
Key Words: Breast; Invasive micropapillary carcinoma; Fine needle aspiration cytology