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HOME > J Pathol Transl Med > Volume 23(4); 1989 > Article
Original Article Ki-1 Positive T-Cell Lymphoma of Bone in a Child.
Hye Seon Ahn, Gil Ro Han, Jin Hee Sohn, Jung Il Suh, Young Hyeh Ko
Journal of Pathology and Translational Medicine 1989;23(4):470-475
DOI: https://doi.org/
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1Department of Pathology, National Medical Center, Seoul, Korea.
2Department of Pathology, School of Medicine, Hanyang University, Seoul, Korea.

Ki-1 monoclonal antibody is a well known marker for Reed-Sternberg cells in Hodgkin's disease, but also occasionally reacts with activated lymphoid cells of either benign or malignant nature. Recently, Ki-1 antibody positive Non-Hodgkin's lymphoma, usually of large cell and/or polymorphous type, has been reported in the lymph nodes, skin, soft tissue, and stomach, but not in the bone. We report a case of multifocal primary bone lymphoma in a seven-year old body involving the left shoulder and right frontal bone, which proved to be a large cell, polymorphous lymphoma, helper T-cell type expressing Ki-1 antigen.

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