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Volume 4(2); December 1993
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Original Articles
A Study on the Identification of Transferrin Type in the Blood Stains
Hee Sul Park, Jin Choe
Korean J Cytopathol. 1970;4(2):77-82.
  • 1,239 View
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AbstractAbstract PDF
Since Smithies demonstrated existence of heritable variation in its molecular structure of transferrin, numerous genetic and anthropological studies have been reported. However there are a few studies of this subject including the distribution of Tf variants among the Korean population. This paper describes the result of distribution of Tf variants among 326 Koreans and also Tf type identified from the blood stains kept under various physical conditions. For the Tf typing, the supernatant solution of the serum by rivanol precipitation method were subjected to disc. electrophoresis following Ornsteins method. The results are summerized in the following:
1. The distribution of Tf type among Korean population is as follows.

Total No. CC BC CD
326 323 2 1
99.1% 0.6% 0.3%

2. The maximum time lapse of blood stains which enable the identification possible, varies with calender month and other conditions as shown in the second table:

Month Condition Identifiable period
July
&
Sept.
Stains on
glass
20 days
cloth 15 days
paper 15 days
mud 7 days
Aug. glass 15 days
cloth 15 days
paper 15 days
mud 7 days
Evaluation of "atypical squamous cells of undetermined significance" by the bethesda system.
Yee Jeong Kim, Sung Ran Hong, Hy Sook Kim, Jong Sook Park, Kye Hyun Kim, Kyung Ho Lim, Jae Uk Shim, Chong Taik Park, Chong Soo Chun
Korean J Cytopathol. 1993;4(2):81-86.
  • 1,404 View
  • 11 Download
AbstractAbstract PDF
No abstract available.
A Study on the Identification of Haptoglobin Types in Blood Stains
Jin Ki Bae, Jin Choe
Korean J Cytopathol. 1970;4(2):85-89.
  • 1,302 View
  • 10 Download
AbstractAbstract PDF
Identification of the serum group from the stains may be of a great significance in the course of crime investigation. A review of world wide literature indicates that a few studies were made on this subject. In this study, the haptoglobin types were identified from the blood stains kept under Korea summer climate. Hp typing was performed by disc. electrophoresis method. The result can be summarized in the following:
1. The maximum time lapse of blood stains, which enable the identification possible, varies with various conditions as shown in the table.

Month Condition Identifiable period
Stains on
glass 15 days
July cloth 7 days
to paper 7 days
Sept. mud 5 days
Morphologic changes of postirradiated cervical cells in cervical cancer.
Hye Kyung Lee, Kwang Min Lee, Dong Kyu Chung, Soo Kon Kim
Korean J Cytopathol. 1993;4(2):87-92.
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AbstractAbstract PDF
No abstract available.
Cytocidal Effect of Immune Lymphocytes on Transplantable Target Tumor Cells (Ehrlich Carcinoma and Sarcoma 180) in Vitro
Soo Young Lee, Young Che Kim
Korean J Cytopathol. 1970;4(2):91-97.
  • 1,130 View
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AbstractAbstract PDF
It is one of remarkable contributions in recent advances on studies of tumor immunity(Klein and Klein, 1962; Prehn, 1963; old and Boyse, 1964). It is most desirable, if immunological treatment by which one can place hope on tumor repression in human subject is adoptive immunization by administration of homologous or heterologous immune lymphoid cells because it has been known that tumor immunity was mostly related to cell-mediated immunity(Coggin, J.H., Larson, V.M., and Hilleman, M.R.,1967). Littman, Kim and Suk (1968) reported that both UV-killed Sarcoma 180 and Ehrlich carcinoma ascites cells are powerfully potent in immunizing the mouse. Kim (1970) in our laboratory reported that the anti-rabbit UV-killed Sarcoma 180 and Ehrlich carcinoma ascites tumor cell-lymphocytes are so effective that both of the solid tumors of mice disappeared completely 30 days after the inoculation of tumors, especially in the group where lymphocytes were injected 14 days after tumor inoculation and the mechanism is the cytotoxic effect of sensitized lymphocytes on the target tumor cells. When this method is applied clinically, it is possible to obtain powerful immune lymphocytes on the target tumor cells by immunization against homologous or heterologous animals. Prior to clinical application, it is desirable to establish the appropriate method of in vitro tumor cell preservation and in vitro cytoxic test for detecting the potency of cell mediated immunity to tumor cells.
Significance of cytologic detection of endometrial carcinoma in papanicolaou smear:the relevance of histologic type, grade and stage.
Sung Ran Hong, Hy Sook Kim, Jong Sook Park
Korean J Cytopathol. 1993;4(2):93-99.
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AbstractAbstract PDF
No abstract available.
Autoradiographic Studies of Early Incorporation of L-Leucine-U-14C into the Liver and the Kidney of Burned Mice
Hoon Suk Song, Young Che Kim
Korean J Cytopathol. 1970;4(2):99-105.
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AbstractAbstract PDF
Since the Cuthbertson’s report that traumatic injuries caused a marked increase of non-protein nitrogen in the urine, it has been generally believed that the traumatic injuries enhanced the catabolism of the body, and this increased catabolism was induced by the secretion of corticoids following trauma. However, it has also been known that traumatic injuries stimulate and increase the anabolism as well as catabolism(Whipple). Investigations have been carried out by the members of our department on the mechanism of the inversion of albumin globulin ratio of plasma protein and the elevation of plasma fibrinogen after burn. According to Lee and Kim(1969), the inversion of albumin-globulin ratio of plasma protein after burn is due to the increased synthesis of albumin and its accelerated "turn-over rate, and the coincidental decreased synthesis of fibrinogen and its retarded turn-over rate. On the other hand, it is well known that both albumin and fibrinogen are produced solely in the liver. Lee(1968) in our laboratories reported that the marked decrease of the incorporation rate of DL-lysine-T(G) into the liver protein in the burned rats, and Kim and Kim (1969) reported that in the burned mice the incorporation rate of L-leucine-U-l4C into the liver protein reached its maximum only 5 minutes after the injection and the curve for the changes of the incorporation rate of L-leucine-U-l4C into the liver protein plotted against time showed the same pattern as in the normal mice. The authors performed the autoradiographic observation on the incorporation rate of L-leucine-U-l4C into the liver cells and the renal tubular cells in both of normal and burned mice, to confirm of Kim’s studies morphologically. The following results were obtained: 1. In the burned mice, the labeled rate of L-leucine-U-l4C into the liver cell reached its maximum later than that in the normal mice, on the other hand, in the renal tubular cells the results were in opposite. 2. In the burned mice, the maximum number of grain of L-leucine-U-l4C reached earlier than that in the normal mice, on the other hand, in the renal tubular cells the inverse results were showed.
Observation on sputum cytology in pulmonary tuberculosis.
In Ae Park, Eui Keun Ham, Sang Kook Lee
Korean J Cytopathol. 1993;4(2):100-104.
  • 2,131 View
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AbstractAbstract PDF
No abstract available.
Fine needle aspiration cytology of follicular neoplasm of the thyroid.
Kyung Ja Cho, Ja June Jang
Korean J Cytopathol. 1993;4(2):105-110.
  • 1,209 View
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AbstractAbstract PDF
No abstract available.
Autoradiographic Studies of Early Incorporation of L-Leucine-U-l4C into Acinar Cells of the Salivary Glands and the Pancreas of Burned Mice
Kong Woo Shin, Young Che Kim
Korean J Cytopathol. 1970;4(2):107-114.
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AbstractAbstract PDF
Since the Cuthbertson’s report that traumatic injuries cause a marked increase of non-protein nitrogen in urine, it has been generally believed that the traumatic injuries enhance the catabolism of the body, and the increased catabolism is induced by the hypersecretion of corticoids following the trauma. However, it has also been reported by some in vestigators that injuries stimulate and increase the anabolism as well as catabolism in the protein metabism. Investigations have been carried out by the members of our department on the mechanism of elevation of plasma fibrinogen after confirmation of its occurrence following the traumatic injuries. They made clear that the inversion of the plasma albumin-globulin ratio of plasma protein after injury was the integral consequence of the decreased albumin amount due to the increased turn-over rate overshadowing the increased anabolism and of the increased fibrinogen amount due to decreased catabolism. Hong(1966) gave traumatic injuries to the pancreas and Im(1966) to the salivary gland, organs which contain large amount of nucleic acid among the body organs, and studied the influence of trauma on enzyme activity and the amount of RNA of those organs and made clear that the traumatic injuries gave rise to a marked increase of amylase activity and amount of ribonucleic acid in the pancreatic cells and a decrease in the amount of ribonucleic acid of the salivary gland. Therefore the authors performed the autoradiographic observation to evaluate the early incorporation rate of L-leucine-U-l4C into the acinar cells of the carotid gland, the sublingual gland and the pancreas of the burned mice. The results were as follows: In the burned mice, the incorporation rate of L-leucine-U-l4C into tile acinar cells of the salivary glands and the Pancreas reached its maximum earlier than that in the normal mice.
Fine needle aspiration cytology of salivary gland lesions.
Seung Sook Lee, In Ae Park, Eui Keun Ham, Sang Kook Lee
Korean J Cytopathol. 1993;4(2):111-120.
  • 1,103 View
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AbstractAbstract PDF
No abstract available.
Total Protein, Paper Electrophoretic Patterns, CRP Reaction and Hemoglobin Content in Lepromatous Leprosy
Jae Sik Kim, Kae Nam Kim, Seong Jik Yoon, Jae Hwan Kim, Jyung Myung Kim
Korean J Cytopathol. 1970;4(2):117-121.
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AbstractAbstract PDF
Total protein, paper electrophoretic patterns, CRP reaction and hemoglobin in lepromatous leprosy cases were tested to estimate recent evaluations compare to past reports. 1. Total protein was 6.99±0.53 gm% in mean value and this result was similar to past reports. 2. In findings of the electrophoretic patterns albumin and α1-, α2-, β-, and γ-globulin were 47.38±0.86%, 6.48±0.94%, 9.54±0.38%, 13.13 ±0.54% and 23.38±0.65% of total protein. From this result of protein fractions, it showed decreased albumin and increased globulin fractions which resulted in decrease of A/G ratio and this result is nearly as same as past reports. 3. There were only 4 cases (8.33%) of positive CRP reaction. 4. The mean value of hemoglobin content was 12.43±0. l7gm%.
Fine needle aspiration cytology of amyloid tumor arising in association with multiple myeloma.
Dong Won Min, Kwang Gil Lee
Korean J Cytopathol. 1993;4(2):121-126.
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AbstractAbstract
No abstract available.
Autoradiographic Studies of Early Incorporation of L-Leucine-U-l4C into the Gastrointestinal Tract of Burned Mice
Wung Jae Park, Young Che Kim
Korean J Cytopathol. 1970;4(2):123-131.
  • 1,097 View
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AbstractAbstract PDF
Florey(1960) and more recently Skoryna(1967) emphasized the intimate relationship between mucin production and peptic ulcer. Skoryna had an idea that "gastric let" or "let mechanism" was the sum of mechanism which protected the gastric wall against mechanical and chemical injuries, and he insisted on the involvement of mucin production in this Mechanism. Selye(1950) reported about gastric ulcer following injuries, but he did not mention mucus secretion in the formation of gastric ulcer in the systemic stress. Kim(1965) revealed that injury induced not only regressive changes in the gastric mucosa but also marked decrease of mucus secretion, and Kim and Kim(1968) applied the autoradiographic technique with radioactive 35S (Na35₂SO₄) to the mucus secretion following systemic injury and demonstrated that injury induced marked regressive changes and also marked decrease of mucin production both in gastric mucosa and rectum. Therefore the authors performed the autoradiographic observation of early incorporation of L-leucine-U-14C into the gastrointestinal tract in both of normal and burned mice in order to confirm that injury may act on protein metabolism of the gastrointestinal tract. The results were as follows: In the burned mice, the incorporation rate of L-leucine-U-14C into the epithelial cells of the mucosa both of the esophagus and the duodenum reached its maximum earlier and that of the stomach, the small intestine and the colon later than those of normal mice. Brunner's glandular cells of the duodeum were enhanced the protein synthesis following injuries.
Fine needle aspiration cytology of Ki-1 positive large cell lymphoma-a case report-.
Kye Hyun Kwon, Jeong Ja Kwak, So Young Jin, Dong Wha Lee
Korean J Cytopathol. 1993;4(2):127-132.
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AbstractAbstract PDF
No abstract available.

JPTM : Journal of Pathology and Translational Medicine