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Brief Case Report
Lipoma within Inverted Meckel's Diverticulum: A Case Report
Su-Mi Kim, Min-Jung Jung, Young-Ok Kim
Korean J Pathol. 2013;47(1):86-88.   Published online February 25, 2013
DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.1.86
  • 6,345 View
  • 56 Download
  • 5 Crossref
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Citations

Citations to this article as recorded by  
  • Pivotal Surgical Intervention for Pediatric Ileoileal Intussusception With Meckel’s Diverticulum: A Case Report
    Dheeraj Surya, Pankaj Gharde, Kavyanjali Reddy, Raju K Shinde, Harshal Tayade, Mihir Patil
    Cureus.2024;[Epub]     CrossRef
  • Intestinal obstruction due to a rare tumor in the meckel's diverticulum in a 10-month-old boy
    Gulan Maree, Mohammad Nasser
    Journal of Pediatric Surgery Case Reports.2022; 79: 102210.     CrossRef
  • A Pediatric Case of Inverted Meckel’s Diverticulum Presenting with Cyclic Vomiting-like Symptoms: A Case Report and Literature Review
    Yoshiko Endo, Keisuke Jimbo, Nobuyasu Arai, Takanori Ochi, Mitsuyoshi Suzuki, Atsuyuki Yamataka, Toshiaki Shimizu
    Children.2022; 9(12): 1817.     CrossRef
  • Inverted Meckel’s diverticulum: a case report 
    Lovenish Bains, Rahul Bhatia, Rohit Kaushik, Pawan Lal, Gayatri Rajpaul, Veerpal
    Journal of Medical Case Reports.2021;[Epub]     CrossRef
  • Adult Intussusception Caused by Inverted Meckel’s Diverticulum Containing Mesenteric Heterotopic Pancreas and Smooth Muscle Bundles
    Seungkoo Lee, Seong Whi Cho
    Journal of Pathology and Translational Medicine.2017; 51(1): 96.     CrossRef
Original Articles
Expression of MUC1 and MUC4 in Gallbladder Adenocarcinoma
Su-Mi Kim, Sun-Ju Oh, Bang Hur
Korean J Pathol. 2012;46(5):429-435.   Published online October 25, 2012
DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.5.429
  • 7,977 View
  • 65 Download
  • 7 Crossref
AbstractAbstract PDF
Background

Recent reports have indicated that overexpression of mucin (MUC) 1 and/or MUC4 correlates with the occurrence and progression of extra-hepatobiliary malignancy. In this study, we investigated the expression of MUC1 and MUC4 and their prognostic significance in gallbladder adenocarcinoma.

Methods

We examined 54 surgical gallbladder adenocarcinoma samples by immunohistochemistry for MUC1 and MUC4 expression. Staining was evaluated as a sum score of extent and intensity, dividing the samples into low and high expression groups.

Results

The low expression group for both MUC1 and MUC4 was 10 samples (18.5%), and the high expression group was 44 samples (81.5%). High MUC1 expression was significantly correlated with more differentiated tumors (p=0.033), whereas high expression of MUC4 correlated with negative nodal status (p=0.012). Other pathological features were not correlated with MUC expression. Multivariate cox regression analysis showed that neither MUC1 nor MUC4 expression correlated with survival.

Conclusions

Although there were some correlations found, a prognostic role for either MUC1 or MUC4 expression in gallbladder carcinoma was not identified in this study. Further investigation is required.

Citations

Citations to this article as recorded by  
  • Environmental and Metabolic Risk Factors Linked to Gallbladder Dysplasia
    Andrei Bojan, Catalin Pricop, Manuela Ciocoiu, Maria Cristina Vladeanu, Iris Bararu Bojan, Oana Viola Badulescu, Minerva Codruta Badescu, Carmen Elena Plesoianu, Dan Iliescu Halitchi, Liliana Georgeta Foia
    Metabolites.2024; 14(5): 273.     CrossRef
  • Expression of Mucoproteins in Gallbladder Cancer
    Puneet Kumar, Priyesh Shukla, Soni Kumari, Ruhi Dixit, Gopeshwar Narayan, V. K. Dixit, A. K. Khanna
    Indian Journal of Surgery.2022; 84(3): 456.     CrossRef
  • Prognostic and clinicopathological value of MUC1 expression in colorectal cancer
    Chao Li, Tao Liu, Libin Yin, Didi Zuo, Yuyang Lin, Lei Wang
    Medicine.2019; 98(9): e14659.     CrossRef
  • Prognostic Significance of Mucin Antigen MUC1 in Various Human Epithelial Cancers
    Feng Xu, Fuquan Liu, Hongwei Zhao, Guangyu An, Guosheng Feng
    Medicine.2015; 94(50): e2286.     CrossRef
  • Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior
    Gi Jeong Kim, Hyungjin Rhee, Jeong Eun Yoo, Jung Eun Ko, Jee San Lee, Hyunki Kim, Jin Sub Choi, Young Nyun Park, Philip C. Trackman
    PLoS ONE.2014; 9(8): e105094.     CrossRef
  • State-of-the-art in the management of locally advanced and metastatic gallbladder cancer
    Mairéad G. McNamara, Cristiane Metran-Nascente, Jennifer J. Knox
    Current Opinion in Oncology.2013; 25(4): 425.     CrossRef
  • Clinicopathological and Prognostic Significance of MUC-2, MUC-4 and MUC-5AC Expression in Japanese Gastric Carcinomas
    Li-Jun Xiao, Shuang Zhao, En-Hong Zhao, Xin Zheng, Wen-Feng Gou, Ya-Nan Xing, Yasuo Takano, Hua-Chuan Zheng
    Asian Pacific Journal of Cancer Prevention.2012; 13(12): 6447.     CrossRef
Clinicopathologic Implications of PIWIL2 Expression in Colorectal Cancer
Sun-Ju Oh, Su-Mi Kim, Young-Ok Kim, Hee-Kyung Chang
Korean J Pathol. 2012;46(4):318-323.   Published online August 23, 2012
DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.4.318
  • 6,692 View
  • 61 Download
  • 33 Crossref
AbstractAbstract PDF
Background

There are no established reports about the expression of the Piwil gene, a subfamily of the Piwi gene involved in RNA silencing and self-renewal, in colorectal carcinomas. It is known that the degree of PIWIL2 expression is higher in colorectal carcinomas. But its clinicopathologic significance remains undetermined. This study reassessed the relationship between PIWIL2 expression and the clinicopathologic parameters in colorectal carcinomas.

Methods

An immunohistochemistry of PIWIL2 expression was done in 60 cases of colorectal carcinoma. This was followed by an analysis of the correlation between PIWIL2 expression and clinicopathologic features and a survival analysis.

Results

There were 44 cases (73.3%) where the degree of PIWIL2 expression was relatively higher. The high degree of PIWIL2 expression was significantly correlated with the lower degree of differentiation (p=0.039), deep invasion (p=0.019) and perineural invasion (p=0.027). The overall survival was longer in patients with the lower degree of PIWIL2 expression than in those with the higher degree of PIWIL2 expression.

Conclusions

Our results showed that the degree of PIWIL2 expression was relatively higher in colorectal carcinomas and it was significantly correlated with variable clinicopathologic indicators for a poor prognosis. This indicates that PIWIL2-positive cells contribute to the progression of colorectal cancer.

Citations

Citations to this article as recorded by  
  • Critical appraisal of the piRNA-PIWI axis in cancer and cancer stem cells
    Elena Garcia-Borja, Frantisek Siegl, Rosana Mateu, Ondrej Slaby, Aleksi Sedo, Petr Busek, Jiri Sana
    Biomarker Research.2024;[Epub]     CrossRef
  • PIWI-interacting RNAs (PiRNAs) as emerging biomarkers and therapeutic targets in biliary tract cancers: A comprehensive review
    Sahar Ahmadi Asouri, Esmat Aghadavood, Hamed Mirzaei, Alireza Abaspour, Mohammad Esmaeil Shahaboddin
    Heliyon.2024; 10(13): e33767.     CrossRef
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    Suman Kumar Ray, Sukhes Mukherjee
    Current Molecular Medicine.2023; 23(4): 300.     CrossRef
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    Melika Ameli Mojarad, Mandana Ameli Mojarad, Bahador Shojaee, Ehsan Nazemalhosseini-Mojarad
    Pathology - Research and Practice.2022; 230: 153757.     CrossRef
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    Mandana AmeliMojarad, Melika AmeliMojarad, Jian Wang
    Cancer Treatment and Research Communications.2022; 31: 100542.     CrossRef
  • Morbid Obesity in Women Is Associated with an Altered Intestinal Expression of Genes Related to Cancer Risk and Immune, Defensive, and Antimicrobial Response
    Ailec Ho-Plágaro, Cristina Rodríguez-Díaz, Concepción Santiago-Fernández, Carlos López-Gómez, Sara García-Serrano, Flores Martín-Reyes, Francisca Rodríguez-Pacheco, Alberto Rodríguez-Cañete, Guillermo Alcaín-Martínez, Luis Vázquez-Pedreño, Sergio Valdés,
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    Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.2022; 1877(5): 188772.     CrossRef
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    Frontiers in Immunology.2022;[Epub]     CrossRef
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    Cancer Cell International.2021;[Epub]     CrossRef
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    Pooneh Mokarram, Maryam Niknam, Mohammadamin Sadeghdoust, Farnaz Aligolighasemabadi, Morvarid Siri, Sanaz Dastghaib, Hassan Brim, Hassan Ashktorab
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  • Identification of Genomic Alterations of Perineural Invasion in Patients with Stage II Colorectal Cancer


    Hao Su, Chen Chang, Jiajie Hao, Xin Xu, Mandula Bao, Shou Luo, Chuanduo Zhao, Qian Liu, Xishan Wang, Zhixiang Zhou, Haitao Zhou
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