Department of Pathology, Ajou University School of Medicine, Suwon, Korea
1Department of Surgery, Ajou University School of Medicine, Suwon, Korea
2Department of Medical Genetics, Ajou University School of Medicine, Suwon, Korea
© 2016 The Korean Society of Pathologists/The Korean Society for Cytopathology
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Case No. | Sex | Age (yr) | Histological type | Tumor diameter (cm) | T stage | N stage | BRAFV600E mutation |
---|---|---|---|---|---|---|---|
1 | F | 49 | Classic | 1 | T3 | N1a | Present |
2 | F | 51 | Classic | 1.2 | T3 | N0 | Present |
3 | M | 43 | Classic | 0.7 | T3 | N1a | Present |
4 | F | 30 | Classic | 0.9 | T3 | N0 | Present |
5 | F | 35 | Classic | 1.2 | T3 | N1a | Present |
6 | M | 48 | Classic | 0.9 | T1a | N0 | Present |
7 | F | 30 | Classic | 1.2 | T3 | N1a | Present |
8 | M | 26 | FVPTC | 1.4 | T3 | N1a | Absent |
9 | F | 60 | Classic | 1.8 | T3 | N1a | Present |
10 | F | 56 | Classic | 1 | T3 | N1a | Present |
11 | F | 63 | Classic | 0.8 | T3 | N1b | Present |
12 | M | 69 | Classic | 1.3 | T3 | N1a | Present |
13 | F | 48 | Classic | 0.8 | T3 | N0 | Present |
14 | F | 59 | Classic | 1 | T3 | N0 | Present |
15 | F | 46 | Classic | 1.5 | T1b | N1a | Present |
16 | F | 62 | Classic | 1.2 | T1b | N0 | Present |
17 | F | 54 | Classic | 1 | T3 | N0 | Present |
18 | F | 63 | Classic | 3.3 | T3 | N1a | Present |
19 | F | 42 | Classic | 0.7 | T1a | N1a | Present |
20 | M | 69 | Classic | 0.8 | T1a | N0 | Present |
21 | F | 52 | FVPTC | 1.2 | T3 | N0 | Absent |
Case No. | Liquid-based cytology |
Histology |
BRAFV600E mutation | ||
---|---|---|---|---|---|
Distribution | Intensity | Distribution | Intensity | ||
1 | 2+ | 3+ | 3+ | 3+ | Present |
2 | 2+ | 2+ | 3+ | 3+ | Present |
3 | 1+ | 1+ | 3+ | 3+ | Present |
4 | 2+ | 2+ | 3+ | 3+ | Present |
5 | 3+ | 3+ | 3+ | 3+ | Present |
6 | 1+ | 2+ | 3+ | 2+ | Present |
7 | 2+ | 3+ | 3+ | 3+ | Present |
8 | 2+ | 2+ | 3+ | 1+ | Absent |
9 | 2+ | 3+ | 3+ | 3+ | Present |
10 | 2+ | 2+ | 3+ | 3+ | Present |
11 | 3+ | 3+ | 3+ | 2+ | Present |
12 | 3+ | 3+ | 3+ | 2+ | Present |
13 | 3+ | 3+ | 3+ | 3+ | Present |
14 | 3+ | 3+ | 3+ | 3+ | Present |
15 | 3+ | 3+ | 3+ | 3+ | Present |
16 | 3+ | 3+ | 3+ | 3+ | Present |
17 | 3+ | 3+ | 3+ | 3+ | Present |
18 | 3+ | 3+ | 3+ | 3+ | Present |
19 | 3+ | 2+ | 3+ | 3+ | Present |
20 | 3+ | 2+ | 3+ | 3+ | Present |
21 | 2+ | 2+ | 3+ | 1+ | Absent |
Distribution of VE1 | ICC |
||
---|---|---|---|
< 30% | 30-80% | > 80% | |
IHC | |||
< 30% | - | - | - |
30%-80% | - | - | - |
> 80% | 2 | 8 | 11 |
Intensity of VE1 | ICC |
||
---|---|---|---|
Weak | Moderate | Strong | |
IHC | |||
Weak | - | 2 | - |
Moderate | - | 1 | 2 |
Strong | 1 | 5 | 10 |
BRAFV600E mutation | VE1 ICC |
VE1 IHC |
||
---|---|---|---|---|
Negative | Positive | Negative | Positive | |
Absence | 0 | 2 | 2 | 0 |
Presence | 1 | 18 | 0 | 19 |
FVPTC, follicular variant papillary thyroid carcinoma.
Distributions of VE1-positive cells: 0+, 0%; 1+, < 30%; 2+, 30%–80%; and 3+, > 80%. Intensities of VE1-positive cells: 0+, none; 1+, weak; 2+, moderate; and 3+, strong.
ICC, immunocytochemistry; IHC, immunohistochemistry.
ICC, immunocytochemistry; IHC, immunohistochemistry.
ICC, immunocytochemistry; IHC, immunohistochemistry.