lgG4-RD and Sjogren's syndrome |
49 |
F |
6,000 |
2,790 |
Anti-SS-A (1:16) |
- |
- |
Chronic hepatitis (3), portal hypertension (2), retroperitoneal ficrosis (1), renal involve (1) |
21.7 |
42.1 |
- |
- |
- |
Yamamoto et al. [47] |
43 |
F |
1,898 |
188 |
Anti-SS-A (1:16) |
- |
- |
- |
- |
- |
- |
- |
48 |
F |
3,009 |
768 |
Anti-SS-A (1:4) |
. |
. |
11.3 |
23.5 |
. |
. |
. |
56 |
F |
1,890 |
694 |
Anti-SS-A (1:16) |
- |
- |
9.7 |
19.4 |
- |
- |
- |
59 |
M |
1,880 |
339 |
Anti-SS-A (1:64) |
- |
- |
- |
- |
- |
- |
- |
73 |
M |
1,912 |
374 |
Anti-SS-A (1:16) |
- |
- |
6.7 |
21.3 |
- |
- |
- |
61 |
M |
2,558 |
774 |
Anti-SS-A (1:16) |
- |
- |
14.7 |
33.4 |
- |
- |
- |
lgG4-RD and Sjogren's syndrome |
62 |
F |
8,478 |
647 |
ANA (1:10,240, homogeneous), anti-SS-A (+), anti-SS-B (+) |
0.92 |
0.82 g/gCr |
General malaise, dry mouth, Raynaud’s phenomenon, anemia, lower extremity weakness, hypergammaglobulinemia |
15 |
- |
No immunoglobulin or complement deposition |
- |
Chronic plasma cell-rich TIN |
Kawano et al. [45] |
lgG4-RD and Churg-Strauss Syndrome |
68 |
F |
1,997 |
275 |
ANCA (–), anti–SS-A (–), RF (+) |
0.9 |
1.2 g/day |
Asthma, multifocal pulmonary infiltrates, marked eosinophilia, a rash on feet, right median nerve paralysis, salivary gland swelling |
- |
10 |
IgG, C3 (granular, capillary), lgG1, lgG4 (+) |
Electron-dense to electron-lucent subepithelial deposits in glomerular capillary walls |
MGN (stage lll-IV) with eosinophil-rich TIN |
Ayuzawa et al. [53] |
IgG4-RD and Lupus nephritis |
71 |
F |
lgG1:1,230, lgG2:735, lgG3:418 |
37.1 |
ANA (1.320 homogeneous) |
9.65 |
2.6 g/day |
Abdominal pain, vomiting, diarrhea, epigastric tenderness, bilateral lower extremity pitting edema, marked leukocytosis, hypoalbuminemia, no skin changes |
13 |
- |
IgG, K, L (2+, granular, mesangial), IgM, IgA, C3 (1+, granular, mesangial) |
Small paramesangial and scattered small electron dense to electron lucent subepithelial and intramembranous deposits |
IgG4-related TIN with MGN, and/or lupus membranous nephritis with TIN |
Zaarour et al. [54] |
ANCA (–), anti–SS-A (–), anti–SS-B (–), anti-dsDNS (–), anti-Sm (–), anti-GBM (–) |