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The Korean Journal of Pathology 2000;34(7): 531-533.
Heterotopic Enchondral Ossification in Metastatic Colonic Adenocarcinoma: A case report .
So Yeon Park, Yong Il Kim, Woo Ho Kim
Department of Pathology, Seoul National University College of Medicine, Seoul 110-799, Korea
Calcification and ossification of colon cancer is frequently encountered, especially in the mucinous carcinoma. However, cartilage formation or enchondral ossification has rarely been described in human colon cancer. This report describes a case of a 59-year-old man with retroperitoneal metastasis of mucinous adenocarcinoma of colon, which showed a widespread heterotopic ossification through membranous or enchondral ossification. The ossification appeared in apposition to tumor cell nests and in the organized mucin pool. In our knowledge, this is the first case showing enchondral ossification in gastrointestinal carcinoma in Korea.
Key Words: Colon; Mucinous adenocarcinoma; Heterotopic ossification; Enchondral ossification