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The Korean Journal of Pathology 2000;34(7): 534-536.
Adenoid Basal Cell Tumor of the Prostate: A case report.
Joo Heon Kim, Woo Sung Moon, Myoung Jae Kang, Dong Geun Lee, Jae Y Ro
1Department of Pathology, Eulji University School of Medicine.
2Department of Pathology, Chonbuk National University Medical School, Institute of Medical Science, Chonju 561-180, Korea.
3Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine.
Adenoid basal cell tumor of the prostate is a rare tumorous lesion that can be misdiagnosed as adenocarcinoma of the prostate. The malignant potential of adenoid basal cell tumor remains uncertain due to small number of reported cases. This 66-year-old man presented with symptoms of urinary tract obstruction. Under the impression of benign prostatic hyperplasia, a transurethral resection of the prostate (TURP) was performed. The patient was alive with no evidence of recurrence or metastasis 15 months after TURP. Microscopically, most of the lesions were composed of nodular collections of small nests of basaloid cells with peripheral palisading, and clusters of tumor cells forming cribriform pattern. Multiple areas of basal cell hyperplasia and atypical basal cell hyperpalsia were also observed. The coexistence of basal cell hyperplasia, atypical basal cell hyperpalsia, and adenoid basal cell tumor with cribriform pattern in this case supports a morphologic continuum from the benign hyperplastic lesion to malignant neoplasia.
Key Words: Adenoid basal cell tumor; Basal cell hyperplasia; Atypical basal cell hyperplasia
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