Human Papillomavirus Prevalence in Gangwon Province Using Reverse Blot Hybridization Assay.

Dongsup Lee; Sunghyun Kim; Sangjung Park; Hyunwoo Jin; Tae Ue Kim; Kwang Hwa Park; Hyeyoung Lee

doi:10.4132/KoreanJPathol.2011.45.4.348

Articles

Page Path: HOME > J Pathol Transl Med > Volume 45(4); 2011 > Article

Original Article Human Papillomavirus Prevalence in Gangwon Province Using Reverse Blot Hybridization Assay.: Dongsup Lee, Sunghyun Kim, Sangjung Park, Hyunwoo Jin, Tae Ue Kim, Kwang Hwa Park, Hyeyoung Lee; Journal of Pathology and Translational Medicine 2011;45(4):348-353
DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.4.348

¹Department of Biomedical Laboratory Science, College of Health Science, Yonsei University, Wonju, Korea. hyelee@yonsei.ac.kr, abba@yonsei.ac.kr
²Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea.

prev next

3,544 Views
30 Download
6 Crossref
6 Scopus

Full Article

Download PDF

Abstract

BACKGROUND
Human papillomavirus (HPV) plays an important role in the development of cervical carcinoma. Although there is a general agreement that high levels of HPV are related to cervical cancer, the prevalence and distribution of HPV genotypes seems to vary by geographical region. This study was designed to investigate the prevalence of HPV genotypes in Gangwon Province, Korea.
METHODS
In total, 342 samples were examined by Pap smear and HPV-ID(R) reverse blot hybridization assay (REBA) (M&D, Wonju, Korea).
RESULTS
Overall HPV positivity was 80.9% and 64.4% in women with abnormal and normal cytology by REBA, respectively. The five most common HPV types were: HPV 16, 53, 58, 56, and 33 in samples with abnormal cytology, and HPV 16, 53, 58, 70, and 18 in samples with normal cytology.
CONCLUSIONS
The REBA can provide useful data regarding prevalence of HPV genotypes. Gangwon Province showed high prevalence of HPV infection in women. The most common HPV type in Gangwon Province was HPV16, and HPV 53, 58, 56, 70 were frequently present.

Keywords: Human papillomavirus;Prevalence;Uterine cervical neoplasms;Reverse blot hybridization assay;Gangwon Province

Figure & Data

References

Citations

Citations to this article as recorded by

Human Papillomavirus (HPV69/HPV73) Coinfection associated with Simultaneous Squamous Cell Carcinoma of the Anus and Presumed Lung Metastasis
Stephanie Shea, Marina Muñoz, Stephen C. Ward, Mary B. Beasley, Melissa R Gitman, Michael D Nowak, Jane Houldsworth, Emilia Mia Sordillo, Juan David Ramirez, Alberto E. Paniz Mondolfi
Viruses.2020; 12(3): 349. CrossRef
Distribution of Oncogenic Human Papillomavirus Genotypes at High Grade Cervical Lesions above CIN 2 Grade with Histological Diagnosis
Geehyuk Kim, Sungyoung Park, Hye-young Wang, Sunghyun Kim, Sangjung Park, Kwangmin Yu, Boohyung Lee, Seung-Ju Ahn, Eun-Joong Kim, Dongsup Lee
Biomedical Science Letters.2016; 22(2): 37. CrossRef
Human Papillomavirus Prevalence and Distribution according to Age among Korean and Chinese Women
Geehyuk Kim, Sunghyun Kim, Sunyoung Park, Sangjung Park, Han Lin, Yubo Ren, Li Yingxue, In Soo Lee, Jae Dal Lee, Dongsup Lee
Korean Journal of Clinical Laboratory Science.2015; 47(4): 259. CrossRef
Comparison of Methods for Measuring Histamine by ELISA and HPLC-MS Assay In Vitro
In Hee Lee, Yoo Hyun Kim
Korean Journal of Clinical Laboratory Science.2015; 47(4): 306. CrossRef
Diagnostic Performance of HPV E6/E7 mRNA and HPV DNA Assays for the Detection and Screening of Oncogenic Human Papillomavirus Infection among Woman with Cervical Lesions in China
Hye-young Wang, Dongsup Lee, Sunyoung Park, Geehyuk Kim, Sunghyun Kim, Lin Han, Ren Yubo, Yingxue Li, Kwang Hwa Park, Hyeyoung Lee
Asian Pacific Journal of Cancer Prevention.2015; 16(17): 7633. CrossRef
Uncommon and Rare Human Papillomavirus Genotypes Relating to Cervical Carcinomas
Na Rae Kim, Myunghee Kang, Soon Pyo Lee, Hyunchul Kim, Jungsuk An, Dong Hae Chung, Seung Yeon Ha, Hyun Yee Cho
Korean Journal of Pathology.2014; 48(1): 43. CrossRef

Cited

Related articles